köken: From Italian madonna, from Old Italian ma (“my”) + donna (“lady”). It was first attested in 1552 and its meaning was primarily (Italian) woman. Its use in the sense of the Virgin Mary was attested much later, in 1844.
köken: Derived, through M(e)a Dom(i)na, from mea (“my, of mine”) + domina (“lady”). By surface analysis, mea + donna. Cognate with Italian and Neapolitan Madonna.